The reference site for Lovastatin

Lovastatin (Merck’s Mevacor) is a statin drug, used for lowering cholesterol in those with hypercholesterolemia to reduce risk of cardiovascular disease.

WHAT IS Lovastatin?

Lovastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.

Lovastatin works by reducing low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.

 

Brand Name(s): Mevacor; Altocor
CAS nº: 75330-75-5
(loe’ va sta tin)

 

Product Info

The sections below will provide you with more specific information and guidelines related to lovastatin and its correct use. Please read them carefully.

FDA Information

Lovastatin was isolated from a strain of aspergillus terreus and it was the first statin approved by the FDA in August 1987.

Why is this medication prescribed?

Lovastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body.

Reducing your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.

Lovastatin also inhibits the production of cholesterol by the liver. It lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the “bad” cholesterol that is primarily responsible for the development of coronary artery disease. By lowering LDL cholesterol levels it can delay progression and may even reverse coronary artery disease.

Other uses for this medicine

Lovastatin may be prescribed for other uses, but it is advised that you ask your doctor or pharmacist for further information.

Dosage and using this medicine

Lovastatin comes in tablets that should be taken by mouth.

Always take lovastatin exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Do not crush or chew the extended-release lovastatin tablets (Altocor®). Swallow them whole, as they are specially formulated to release the medication slowly in the body.

For the greatest effect, lovastatin is usually taken at bedtime or with an evening meal. If you take lovastatin several times daily, take it with meals and follow your doctor’s directions.

Your doctor may want to monitor your liver function with blood tests before starting treatment with lovastatin, at six and twelve weeks after both the start of your treatment and any increase in dose, and periodically (every 6 months) thereafter. Depending on the results of these tests, your doctor can determine how much monitoring you will require.

Grapefruit and grapefruit juice may interact with lovastatin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

Eat a low-fat, low-cholesterol diet. To see beneficial effects from lovastatin, avoid fatty, high-cholesterol foods.

It is important to take lovastatin regularly to get the most benefit from it.

Do not stop taking lovastatin without first talking to your doctor. Lovastatin may need to be taken on a long-term basis for the treatment of high cholesterol.

Lastly, your doctor may want you to have blood tests or other medical evaluations during treatment with lovastatin to monitor progress and side effects.

What special precautions should I follow?

Before taking Lovastatin:

Tell your doctor if you have kidney disease, have a chronic muscular disease or have a blood disorder. You may not be able to take lovastatin, or you may require a dosage adjustment or special monitoring during treatment, if you have any of the conditions listed above.

Do not take lovastatin without first talking to your doctor if you have liver disease.

Alcohol and lovastatin can both be damaging to the liver. Alcohol should be used only in moderation and it is advised that you discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.

Lovastatin is in the FDA pregnancy category X. This means that lovastatin is known to cause birth defects if it is taken during pregnancy. Do not take lovastatin if you are pregnant or could become pregnant during treatment.

Additionally, it is not known whether lovastatin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

What should I do if I forget a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.

Do not take a double dose of this medication.

What side effects can this medication cause?

Side effects from lovastatin include:

stomach upset
nausea
constipation
diarrhea

Tell your doctor if any of these symptoms are severe or do not go away:

stomach pain or cramps
diarrhea
constipation
heartburn
blurred vision
dizziness
rash or itching

If you experience any of the following symptoms, call your doctor immediately:

signs of an allergic reaction (hives, difficulty breathing, swelling of your face, lips, tongue, or throat)

Lovastatin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Remember to throw away any medication that is outdated or no longer needed. If you have any queries, please talk with your pharmacist about the proper disposal of your medication.

In case of an emergency/overdose

In the case of an overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

nausea
diarrhea
stomach distress
indigestion

NB: An overdose of lovastatin is not expected to produce life-threatening symptoms.

Product Images

PICTURES OF LOVASTATIN PILLS

Below you will find images and specific information on the principal types of lovastatin that exist, including their respective brand name(s), strength, inscription codes and manufacturers.

The information below includes general information and guidelines for patients taking this medication and should never be used to substitute professional medical advice that can be provided by a qualified physician or family doctor.

Name: LOVASTATIN
Strength(s): 10 MG
Imprint: E 70
Manufacturer: EON LABS.

Name: LOVASTATIN
Strength(s): 10 MG
Imprint: M L19
Manufacturer: MYLAN

Name: LOVASTATIN
Strength(s): 10 MG
Imprint: GG 770
Manufacturer: SANDOZ

Name: LOVASTATIN
Strength(s): 10 MG
Imprint: 926 | 93
Manufacturer: TEVA USA

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: E 72
Manufacturer: EON LABS.

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: M L20
Manufacturer: MYLAN

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: G | LV 20
Manufacturer: PAR PHARM.

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: R | 634
Manufacturer: PUREPAC PHARM.

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: GG 226
Manufacturer: SANDOZ

Name: LOVASTATIN
Strength(s): 20 MG
Imprint: 93 | 576
Manufacturer: TEVA USA

Name: LOVASTATIN
Strength(s): 40 MG
Imprint: 93 | 928
Manufacturer: ALLSCRIPTS

Name: LOVASTATIN
Strength(s): 40 MG
Imprint: R | 635
Manufacturer: ALPHARMA US.

Name: LOVASTATIN
Strength(s): 40 MG
Imprint: E 74
Manufacturer: EON LABS.

Name: LOVASTATIN
Strength(s): 40 MG
Imprint: M L21
Manufacturer: MYLAN

 

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